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Peripheral I.V. catheters are peripheral venous devices used to infuse medication or fluids directly into a vein, or draw blood samples for testing. These catheters are made of a non-irritant material, such as silicone, which negates any side effects caused when they are left in the patient's arm for several weeks or months. Peripheral I.V. catheters are introduced into the peripheral vein using a needle and fixed to the patient's skin with an adhesive tape. The needle is then removed, leaving a small tube of the cannula at the insertion site. Advanced peripheral I.V. catheters are equipped with additional safety features to prevent needlestick injuries, which allow for their use in critical care units in hospitals.