Hillary Clinton takes it all in her stride.

The former Secretary of State appeared non-plussed as a woman hurled a shoe at her in protest, as Clinton delivered a speech at a hotel in Las Vegas.

Clinton crouched to dodge the flying object as she stood on stage and continued with her remarks.

The protester had been denied access to the event but had pushed past security, she was later taken into custody by the Secret Service and hotel security.

The former First Lady, who is said to be thinking about running for president again, joked about the incident as she talked to around 1,000 people attending a metal recycling conference.

"Is that somebody throwing something at me?" Clinton asked, according to media reports. "Is that part of Cirque du Soleil?"

"My goodness, I didn't know that solid waste management was so controversial," she added.