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Man Utd: Barthez, Irwin, Silvestre, Stam, Gary Neville, Beckham, Giggs, Keane, Butt, Sheringham, Cole. Subs: Van Der Gouw, Phil Neville, Yorke, Solskjaer, Chadwick.
West Ham: Hislop, Tihinen, Stuart Pearce, Dailly, Schemmel, Winterburn, Lampard, Cole, Carrick, Kanoute, di Canio. Subs: Forrest, Potts, Moncur, Ian Pearce, Soma.
Referee: P Durkin (Dorset).
Manchester United 0-1 West Ham United
A goal from Paolo di Canio knocked Manchester United out of the FA Cup as West Ham beat the odds at Old Trafford.
The Italian struck in the 76th minute, latching onto Frederic Kanoute's through ball and beating the protesting Fabien Barthez, who looked in vain for the offside flag.
Man Utd finished the game with four strikers on the field - Dwight Yorke and Ole Gunnar Solskjaer joining Andy Cole and Teddy Sheringham - but still failed to find a equaliser.
Di Canio's winner ended a run which had seen West Ham fail to win at Old Trafford since 1986.
The result also made a mockery of their problems in their build-up to the game, their squad decimated by injuries and international call-ups.
Kanoute, and goalkeeper Shaka Hislop were only playing after passing late fitness tests but still looked to be feeling the effects of their respective calf and knee injuries.
Hislop's problems were notably apparent as Stuart Pearce took West Ham's goal-kicks.
Hislop mis-kicked an attempted clearance after 14 minutes but a back-tracking Tihinen was on hand to clear the danger.
But Hislop, like his team-mates, was putting up a determined resistance as the home side began to increase the pressure after a low-key opening.
A minute after Ryan Giggs had produced a sparkling piece of skill to create a crossing opportunity, Hislop turned away an angled shot from the Welshman.
Giggs frustrated
Giggs was involved in most of the home side's best efforts but failed to apply the finishing touch to a sweeping counter-attack after 33 minutes.
Hislop was proving a determined obstacle to overcome and tipped over a David Beckham free-kick before Sheringham was guilty of spurning a glorious opportunity.
After Hislop had parried an Andy Cole shot, Sheringham shot over with a gaping goal at his mercy.
A stinging Joe Cole 25-yard shot was parried by Barthez as West Ham showed they attacking potential.
But the Frenchman could not keep out di Canio's effort as the game looked to be heading for a replay.
Paolo Di Canio (born 9 July 1968) is an Italian football manager and former professional footballer. During his playing career he made over 500 league appearances and scored over one hundred goals appearing primarily as a forward but could also play as an attacking midfielder, or as a winger. A talented yet controversial player, Di Canio was known for his creativity, technical ability, and dribbling skills, as well as his tenacity and aggression on the pitch.
Di Canio began his career in the Italian Serie A, playing for Lazio, Juventus, Napoli and A.C. Milan, before a brief spell with the Scottish club Celtic. He subsequently spent seven years in the English Premier League with Sheffield Wednesday, West Ham United and Charlton Athletic. He returned to Italy in 2004, playing for Lazio and Cisco Roma before retiring in 2008. He played for the Italian under-21s, making 9 appearances and scoring 2 goals, and was notably a member of the squad that finished in third place at the 1990 UEFA European Under-21 Championship under manager Cesare Maldini, but was never capped for the senior team.