In this video, CancerBro will explain the treatment for non-metastatic pancreatic cancer.

Video Transcript:

Now we will discuss the resectability of the pancreatic tumor, depending upon the extent of tumor.

Tumor located within the pancreas, without extension to adjacent structutes, is considered to be resectable.

This figure shows a resectable tumor located in the head of pancreas. Similarly, this is a resectable tumor located in the tail of pancreas.

A tumor located in the head of the pancreas, that extends to involve the duodenum, is also considered to be resectable.

Similarly, tumors arising from the tail of pancreas, that involve the spleen, left kidney, or left suprarenal gland, may also be resected.

Superior mesenteric vein involvement maybe considered resectable, boderline resectable or unresectable, depending upon the extent of arterial involvement.

Similarly, involvement of portal vein maybe considered resectable, borderline resectable or unresectable, depending upon the extent of arterial involvement.

Infiltration of tumor into common hepatic artery only, is borderline resectable in most of the cases.

Infiltration of tumor into the superior mesentric artery maybe considered borderline resectable or unresectable, depending upon the extent of arterial involvement.

Celiac artery involvement may also be borderline resectable or unresectable, depending upon the extent of arterial involvement.

Now we will discuss the treatment for all the three, that is resectable, borderline resectable, and unresectable disease.

Surgery is the treatment of choice of resectable disease, but chemotherapy may be added rarely for some high risk patients.

For borderline resectable patients, chemotherapy with or without radiotherapy is used, and then the decision for surgery is taken, depending upon the response to treatment.

And for unresectable patients, chemotherapy is the treatment of choice, and radiotherapy maybe used very rarely.

The final decision is taken by the oncologist, on an individual patient basis, depending upon the performance status of the patient and exact stage of the disease.


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