http://www.oramd.com/periodontaldisease/3-causesofperiodontalproblems.htm Periodontal disease, heart disease - both are serious diseases that afflicts many people. The symptoms of periodontal disease are inflamed, irritated, red, sensitive, gums that bleed readily. Periodontal disease is in itself uncomfortable and can lead to even worse mouth conditions such as mouth ulcers, the loss of teeth, and even heart disease.