Louisville vs. Clemson: The 2nd-ranked Tigers did not mess around Saturday afternoon against the Cardinals, winning 77-16. Clemson running backs Travis Etienne and Tavien Feaster both rushed for more than 100 yards and 3 combined touchdowns. Tigers linebacker Isaiah Simmons returned an interception for a touchdown and defensive lineman Dexter Lawrence got a rare rushing attempt that he plunged into the end zone for a score. Louisville wide receiver Jaylen Smith caught 5 passes for 63 yards in the loss.