Deep in the Amazon, intrepid riverboat captain Frank Wolff (Dwayne Johnson) forms an unlikely partnership with Dr. Lily Houghton (Emily Blunt), a sharp and charming researcher from London intent on studying a fabled tree with remarkable healing properties. As Frank and Lily navigate the risks of the rainforest's uncharted wilderness, the pair come up against a cohort of sinister foes determined to use the tree for nefarious purposes. Inspired by the theme park ride at Disneyland. Directed by Jaume Collet-Serra. Co-starring Edgar Ramírez, Jesse Plemons, and Paul Giamatti.