Lee Dawson, 42, suffered fatal knife wounds when he was viciously attacked in Jutland Street in June 2022.
Benjamin Bibby, 21, of Dawson Walk, Preston, and Andrew Wilcock, 29, of Lincoln Walk, Preston, were found guilty of murder by a jury at Preston Crown Court following a three-week trial.
They were both jailed for life with a minimum of 24 years on Tuesday (February 14).
Robert Cross, 34, of Milner Street, Preston, was convicted by the jury of Mr Dawson’s manslaughter but cleared of murder.
He was jailed for 15 years.
Kerry-Anne Metcalf, 39, of Dawson Walk, Preston was found guilty of assisting an offender.
She was jailed for 15 months.