The hideously mutilated body of DEA Agent Enrique "Kiki" Camarena sparks the largest manhunt in the Drug Enforcement Administration's history.

Implicated in his murder is the Godfather of Mexican drug lords himself, Miguel Angel Felix Gallardo. But the subsequent homicide investigation also exposes widespread corruption and a cover-up within the highest levels of the Mexican government. It would take a special unit of investigators, a battalion of Mexican soldiers and months of undercover work by the DEA to bring the killers of their fallen comrade to justice.