The five largest U.S. lottery jackpots on record include a $2.04 billion Powerball win in California (Nov. 7, 2022), a $1.787 billion Powerball split in Missouri and Texas (Sept. 6, 2025), a $1.765 billion Powerball win in California (Oct. 11, 2023), a $1.602 billion Mega Millions win in Florida (Aug. 8, 2023), and a $1.586 billion Powerball shared across three states (Jan. 13, 2016). These historic wins turned everyday players into instant multimillionaires and continue to spark fascination for their improbable outcomes.