Novo Nordisk makes its first-ever Super Bowl appearance with “A New Way,” a star-studded commercial for the newly approved Wegovy oral weight-loss pill that blends humor with a serious message about normalizing medical support for weight management. The 90-second spot begins with Kenan Thompson breaking the news that Wegovy now comes in pill form and asking viewers whether, if life’s challenges could be made easier with a pill, they’d take it — setting up a series of comedic scenarios. From John C. Reilly struggling to parallel park and DJ Khaled imagining a wrestling-pills dream, to Danielle Brooks, Ana Gasteyer and Danny Trejo each playing with the idea of “easy fixes,” the spot uses levity to cut through stigma and start honest discussions around weight, health and the role GLP-1 medications can play alongside lifestyle changes.

Does Wegovy’s Super Bowl LX message about honest weight-loss conversations and reducing stigma land for you?
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