Listen towards the end, he admits his agenda is unpopular!!!

Ed Henry: "Can you envision a scenario where you don't run for re-election?"
Obama: "Here's how I think about it, I said to myself very early on, even when I started running for office, that I don't want to be make decisions based on getting re-elected because the challenges that face America are so significant...If I feel like I've made the very best decision for the American people and 3 years from now I look at it and my poll numbers are in the tank because we have gone through these wrenching changes, politically I'm in a tough spot, I'll feel alright about myself...