Oscar Pistorius said Wednesday he is targeting breaking the 45-second barrier in the 400m as he prepares to become the first double amputee athlete to compete in the able-bodied Olympics. The South African, known as 'Blade Runner' because he runs with carbon fibre prosthetic running blades, competed in the Athens 2004 and Beijing 2008 Paralympics. But the 25-year-old can now make his debut in the Olympics following studies that found his prosthetics give him no advantage over his able-bodied rivals. Duration: 01:17