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During the forecast period from 2012-2022, the growth of the UC market will be driven largely by the entry of Johnson & Johnson’s (J&J’s) Simponi and Takeda’s Entyvio, which will lead to an increase in the overall number of patients being treated with biologics in the US, 5EU, Japan, and Canada. Another key event affecting the UC market is the anticipated launch of biosimilars, given that the patent expiry of the UC blockbusters, Remicade and Humira are set to expire in the US in 2018 and 2016, respectively.
It is worth noting that in India, the local drug companies produce their own biosimilars, without many regulatory guidelines or any regard for the patent protection of the marketed products. For the treatment of UC, Indian physicians rely heavily on non-pharmacological methods, such as dietary recommendations, and for pharmacologic therapy, they use generic products within the corticosteroids and 5-ASA classes. Researcher physician survey showed that these drugs are the mainstay of treatment for mild to moderate UC in India, as well as at earlier lines of therapy for severe disease.